Ankle-Arm Index is a Useful Test for Clinical Practice in Outpatients With Suspected Coronary Artery Disease(Clinical Investigation)
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概要
- 論文の詳細を見る
Background Although a low ankle-arm index (AAI) has been reported to be associated with increased risk of cardiovascular mortality in several populations, no data exist concerning the impact of AAI for outpatients with suspected coronary artery disease (CAD) in the clinical setting. Methods and Results The present study enrolled 840 outpatients (age range 35-87 years, mean age 63.9±10.2) with suspected CAD. All patients underwent AAI measurements and coronary angiography, and based on the AAI values, they were divided into group A (AAI <0.9; n=191; CAD positive, 181) and group B (AAI ≥0.9; n=649; CAD positive, 509). Metabolic syndrome (MS), obesity, and level of the inflammatory biomarker high sensitive C-reactive protein (hsCRP) were compared between the 2 groups. The sensitivity, specificity, positive and negative predictive values in predicting CAD with an AAI value <0.9 in all patients were 26.2%, 93.3%, 94.8% and 21.6%, respectively. The patients in group A was significantly older and there was a higher femaleto-male ratio than in group B. The presence of hypertension and diabetes mellitus, current smoking status, and levels of low density lipoprotein (LDL)-cholesterol level, uric acid and hsCRP differed significantly between the 2 groups. Group A had a higher percentage of high LDL-cholesterol level, high waist-to-hip ratio and more positive cases of MS than group B. Multivariate logistical regression analysis showed that AAI was related to MS, high levels of hsCRP (>3mg/L) and uric acid (>7mg/dl) with odds ratios of 1.769, 3.907 and 2.580, respectively. Conclusions The AAI test is an effective tool in predicting CAD in outpatients in clinical practise.
- 社団法人日本循環器学会の論文
- 2006-05-20
著者
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Yang Teng-yao
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Hung Kuo-chun
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Chang Shih-Tai
Divisions of Cardiology, Chiayi Chang Gung Memorial Hospital
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Chen Chien-Lung
Division of Internal Medicine
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Chu Chi-Ming
Section of Health Informatics, Institute of Public Health, National Defense Medical Center and Unive
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Lin Pi-Chi
Divisions of Cardiology, Chiayi Chang Gung Memorial Hospital
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Chung Chang-Min
Divisions of Cardiology, Chiayi Chang Gung Memorial Hospital
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Hsu Jen-Te
Divisions of Cardiology, Chiayi Chang Gung Memorial Hospital
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Cheng Hui-Wen
Divisions of Cardiology, Chiayi Chang Gung Memorial Hospital
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Chu Chi-ming
Section Of Health Informatics Institute Of Public Health National Defense Medical Center And Univers
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Lin Pi-chi
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Hsu Jen-te
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Cheng Hui-wen
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Chang Shih-tai
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Chung Chang-min
Divisions Of Cardiology Chiayi Chang Gung Memorial Hospital
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Hsu Jen-te
Division Of Cardiology Chang Gung Memorial Hospital Chiayi & Chia-yi School Chang Gung Institute Of Technology
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Hung Kuo-chun
Division Of Orthopedic Surgery Chang Gung Memorial Hospital Chiayi & Chia-yi School Chang Gung Institute Of Technology
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Chang Shih-tai
Division Of Cardiology Chang Gung Memorial Hospital Chiayi & Chia-yi School Chang Gung Institute Of Technology
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Lin Pi-chi
Division Of Cardiology Chang Gung Memorial Hospital Chiayi & Chia-yi School Chang Gung Institute Of Technology
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Chung Chang-Min
Division of Cardiology, Chiayi Chang Gung Memorial Hospital, Chang Gung University College of Medicine
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