Radioimmunoassayによる血中dextranaseの測定について第1報

概要

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Dextranase labelled with^<125> Iodine was applied by means of a radioimmunoassay to detect any change in the permeability of the oral mucosa under test. For the purpose of this experiment, two groups were selected: Group one contained three individuals with clinically healthy gingivae. Group two contained six individuals with periodontally diseased gingivae. The treatment was undertaken using different concentrations of the dextranase solution. The maximum effective concentration was twenty five nano-grames of dextranase to one millilitre of water (25 ng/ml) (B/Bo=90 percent) There was no remakable change in the condition of either the control or the diseased cases. Nor was there any significant improvement in the cases with periodontally diseased gingivae. Moreover, the dextranase was not found to cause any senitive reaction in the human body.
特定非営利活動法人日本歯周病学会の論文
1978-06-28