歯周病菌肉のPlasmin系物質,とくにその活性度の測定法について

概要

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In general understanding, the plasmin has fibrinolytic action, so the blood coagulum is disolved with the existence of plasmin. Also, the plasmin acts not only to the fibrin but to the series of coagulation factors and result is bleeding phenomenon. The bleeding from gingiva is the symptom frequently observed in periodontal diseases. Evaluation of the relationship between plasmin series substances and gingiva of periodontal diseases is usually done by studing fibrinolysis series by means of fibrin plate method. The author performed the experiment with the same means of study but in a modified way. The piece of gingiva was put on the plate instead of using the exudate. The advantage of the present method is that the fibrinolysis activity of the plasmin series substances in gingiva is measured by simply using the biological material, and does not require a complicated method to obtain the extracted solution. In conclusion,the activator was recognized in gingiva of periodontal disease. The gingiva of periodontal disease with the blood upon operation, however, may have the plasmin activity or only the activities of the activator.
特定非営利活動法人日本歯周病学会の論文
1967-06-30