Hepatoprotective and Immunological Effects of Antioxidant Drugs
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概要
- 論文の詳細を見る
The hepatoprotective and immunomodulatory effects of silymarin and amino-imidazole-carboxamide-phosphate were studied in 40 patients with alcoholic cirrhosis of the liver in a one-month doubleblind clinical trial. Treatment with either of the drugs normalized the elevated levels of aspartate aminotransferase, alanine aminotransferase and serum bilirubin, markedly reduced the high level of gamma-glutamyl transferase, increased lectin-induced lymphoblast transformation, decreased the percentage of OKT8^+ cells and suppressed lymphocytotoxicity. None of these changes occurred in the placebo-treated group. Thus, the hepatoprotective effects of silymarin and amino-imidazole-carboxamide-phosphate in alcoholic cirrhosis can partly be attributed to the immunomodulatory activity of the drugs.
- 東海大学の論文
- 1990-03-08
著者
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Lang Istvan
Second Department Of Medicine Semmelweis University Medical School
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Feher Janos
Second Department Of Medicine Semmelweis University Medical School
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Gergely Peter
Second Department Of Medicine Semmelweis University Medical School
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Gergely Peter
Second Department Of Medicine Semmelweis University Budapest And Buda District Children's Hospi
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Lang Istvan
National Institute Of Oncology Budapest
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NEKAM Kristof
Second Department of Medicine, Semmelweis University Medical School
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MUZES Gyorgyi
Second Department of Medicine, Semmelweis University Medical School
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GONZALEZ-CABELLO Rhenzo
Second Department of Medicine, Semmelweis University Medical School
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Muzes Gyorgyi
Second Department Of Medicine Semmelweis University Medical School
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Nekam Kristof
Second Department Of Medicine Semmelweis University Medical School
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Gonzalez-cabello Rhenso
Second Department Of Medicine Semmelweis University Medical School
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