Hodgkin's Disease : In Vitro Susceptibility of Skin Fibroblasts to Infection with Virus and to Lysis by Autologous Lymphocytes

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概要

• 論文の詳細を見る

• Fibroblast cultures established from the skin of 16 untreated stage 1 and stage 2 Hodgkin's patients (HD) and 60 healthy controls were studied in their 3rd, 4th and 5th in vitro passage. HD cultures were similar to control cultures with respect to transformation with Simian sarcoma virus (SSV) and SV_<40> and with respect to interferon release. HD cultures, howerver, showed a depressed replication of both herpes simplex virus (HSV) type 1 and type 2. Preliminary evidence for enhanced immune interaction with fibroblasts in HD was a more frequent injury of HD than control fibroblast cultures when incubated 4 hours with autologous mononuclear leucocytes in the presence of autologous serum.

• 東海大学の論文
• 1980-09-13

著者

• Olsson L.

  Institute Of Medical Microbiology University Of Copenhagen

• Ebbesen P.

  Institute Of Medical Microbiology University Of Copenhagen:institute Of Cancer Research Radiumstatio

• VESTERGAARD B.

  Institute of Medical Microbiology, University of Copenhagen

• TING R.

  Biotech Research Laboratory

• HAAHR S.

  Institute of Medical Microbiology, University of Aarhus

• Haahr S.

  Institute Of Medical Microbiology University Of Aarhus

• Vestergaard B.

  Institute Of Medical Microbiology University Of Copenhagen

関連論文

• Hodgkin's Disease : In Vitro Susceptibility of Skin Fibroblasts to Infection with Virus and to Lysis by Autologous Lymphocytes

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