Abnormal Topological Distribution of Surface Glycoprotein on Neoplastic Epithelial Cells(PROPERTIES OF CELL SURFACE PROTEIN)

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概要

• 論文の詳細を見る

• Immunohistochenically, carcinoembryonic antigen (CEA) was found at the apex and secretory component (SC) on the basal lateral surface of normal colonic epithelial cells. On neoplastic colon cells, both glycoproteins when present were distributed all around the cells. Little or no CEA and SC were found on normal gastric epithelial cells. CEA and SC apeared on intestinal metaplastic cells in a pattern similar to that of the normal colonic epithelim. In gastric carcinoma, both glycoproteins when present were found all around the neoplastic cells. The observations suggest that neoplstic transformation of epithelial cells is accompanied by a loss of the normal polar distribution of surface glycoproteins.

• 東海大学の論文
• 1982-06-14

著者

• Brown William

  University of Colorado at Denver and Health Science Center

• Brown William

  University Of Colorado School Of Medicine

• Nakane Paul

  Tokai University School Of Medicine

• NAGURA Hiroshi

  Veterans Administration Hospital

• Nagura Hiroshi

  Veterans Administration Hospital:department Of Pathology Tokai University School Of Medicine

関連論文

• Modifiable Risk Factors for Colorectal Neoplasms and Hyperplastic Polyps
• The Central Role of the Gastrointestinal Tract in Immunological Reactions
• Abnormal Topological Distribution of Surface Glycoprotein on Neoplastic Epithelial Cells(PROPERTIES OF CELL SURFACE PROTEIN)

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