病理組織標本の観察を快適にする新規油浸操作法の開発

概要

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The observation of histopathological samples is a generic technology which is very important in the diagnosis of various diseases. There are many cases in which the oil-immersion operation is required, namely the specimen is observed at the maximum magnification. The oil-immersion operation has brought about a major contribution for the development of the pathology. However, the immersion oil for this operation contaminates the tip of objective lens in the oil-immersion system, and it often becomes a reason of damaging the lens. It is proposed that the use of anisole for the oil-immersion operation can solve this problem by some scholars in clinical test laboratory. As a result, adverse effect to the lens can be drastically reduced, since the anisole adhered to the objective lens is easily volatilized because of its low boiling point. However, the offensive odor of anisole can cause health hazards, and, moreover, it is flammable. In order to mitigate those defects, we developed an oil-immersion operation method using lavender oil. The adverse effect on human body and also on the objective lens can be drastically reduced without sacrificing the microscopic resolution. The authors expect our novel oil-immersion method can contribute to the development of histopathology and microbiological tests.
2004-03-31