誘電特性を用いた腸管のviability判定に関する実験的検討

概要

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Background : This study aimed at establishment of evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. Methods : In the rats, the 20 cm segment of the distal ileum and mesentery with the blood vessels were strangulated with compression device consisting of an acrylic ring and a balloon. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 minutes. The conductance and capacitance obtained by impedance analyzer were used to calculate %tan δ m in the strangulated intestine. ATP was measured as well. In another experiment, after the various periods of strangulation, %tan δ m was measured just before release of the strangulation. Rats were divided into Group A (survived for 7 days) and Group D (died within 6 days). Results : There was a positive correlation between %tan δ m and ATP levels (R=0.80). Additionally, %tan δ m was significantly more in Group A than in Group D (p<0.05). There was no death at 80 % or more in %tan δ m, and was no survival at less than 74 % in % tan δ m except for two rats. Conclusions : These results suggested that %tan δ m may be a useful index of the viability of the strangulated intestine before reperfusion.
岐阜大学の論文
2003-03-31