γ-メタクリロキシプロピルトリメトキシシランをグラフトしたシリコーンエラストマーの細胞適合性(<ゲストエディターによる特集>周期空間と相互作用する新しいセラミックスのマテリアルデザインとプロセッシング)

概要

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γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted on a silicone elastomer by emulsion polymerization in order to improve cytocompatibility. The wettability of the grafted surface was evaluated with a contact angle toward distilled water. By grafting within 30 min at 60℃, the contact angle was reduced from 110° to about 70° while it remained almost constant for longer grafting. A larger number of osteoblastic cells (MC3T3-E1) and fibroblast cells (L929) proliferated on the surface modified with γ-MPS compared with the original silicone surface. After culturing for 7 d, the cells completely covered the grafted surface and even formed a cell layer.
社団法人日本セラミックス協会の論文
2006-01-01