Intrinsic Fiber-Optic Immunosensors Based on Monochromatic Light Excitation of Surface Plasmon Resonance

概要

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Currently, the intrinsic fiber-optic immunosensors in common use are usually based on polychromatic a light excitation of the surface plasmon resonance, such as the BIACORE Probe developed by Biacore company (Sweden). We propose in this paper a novel fiber-optic immunosensor, simpler and cheaper, which is illuminated by a monochromatic light at 658 nm wavelength emitted from a commercialy available laser diode. The application of detecting the rabbit IgG affinity reaction proves its feasibility. This work provides a starting step towards the development of a portable immunoprobe for non-labeling immunoassay.
社団法人応用物理学会の論文
2000-09-15