膀胱癌の化学療法 : 全剔除膀胱癌に対する制癌剤局所投与による影響

概要

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For the purpose of correct judgment for the effect of anti-cancer agents and improving the prognosis of vesical cancer treated operatively and chemotherapeutically, it was observed histopathologically how anti-cancer agents, i.e. Carzinophilin, Mitomycin C and Thio-TEPA, administrated individually, influenced on vesical cancer in 15 patients whose tumors had been very extensive and in high grade having need of total cystectomy. And their results could be summarized as below. 1) Topical administration of anti-cancer agents on vesical cancer is effective. 2) Concerning the dosage and the duration, in early stage, administration of rather small dose in short duration can obtain good effects but in late stage needing total cystectomy, large dose in long duration can do.
社団法人日本泌尿器科学会の論文