皮弁の組織伸展性に関する病理組織学的研究
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Utilizing a groin flap of a rat, a free flap and pedicled island flap study models were constructed and the effects of tissue expansion with tissue expander were investigated histopathologically. The thickness of the epithelium was measured with the CAS 200 image analyzer system. The epithelium of the free and pedicled island flaps was grouped into the expanded and non-expanded groups. 1)Immediately after placement and fixation of the tissue expander, strong inflammation of the epidermal tissues of the free flap was noticed but after commencement of tissue expansion, there were no evident difference observed between the free flap and pedicled island flap. 2)The thickness of the dermis and the capsule adjacent to the embedded tissue expander decreased with time, as the tissue was expanded. 3)With tissue expansion, it was evident that the thickness of the corium decreased and flattening of the blood vessels and epidermal layers, laceration of the collagen fibers, destruction of the vessel walls, and loss of function of the epidermal layers were not observed. From the above stated findings, concerned with the free flap, if rapid tissue expansion is conducted without applying extreme stress to the site of transplantation and by maintaining sufficient circulation, we believe tissue expansion during the early post-operative period is possible as is with the pedicled island flap. As revealed, the importance of the tissue expander, prevention of post-operative contracture of the reconstruction flaps after tissue and/or utilization of tissue expansion makes it possible to obtain sufficient space for a secondary bone graft where space is scarce.
- 福岡歯科大学学会の論文
- 2002-03-31
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- 皮弁の組織伸展性に関する病理組織学的研究