Proteoglycans of Cartilage Extracellular Matrix(<Special>Advances in Connective Tissue Research in Bone and Joint)

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概要

• 論文の詳細を見る

• Cartilage is localized on the surface of joint and helps joint movement. During development, cartilage serves as template for bones. Extracellular matrix of cartilage contains two major structures: fibrils and fibers of collagens, and the proteoglycan aggregates. Other matrix molecules, interacting each other, contribute to formation of a highly integrated structure of cartilage. Cartilage contains a variety of proteoglycans including aggrecan, versican, perlecan, and small leucine-rich proteoglycans. Recent studies using knockout mice of these proteoglycans revealed their in vivo functions. In this review, roles of these proteoglycans in cartilage development and its homeostasis are discussed.

• 日本結合組織学会の論文
• 2000-09-25

著者

• WATANABE Hideto

  Institute for Molecular Sciences of Medicine, Aichi Medical University

• Watanabe Hideto

  Institute For Molecular Science Of Medicine Aichi Medical University

関連論文

• Ultrastructural immunolocalization of a cartilage-specific proteoglycan, aggrecan, in salivary pleomorphic adenomas
• Characterization of an Anti-Decorin Monoclonal Antibody, and Its Utility
• The Proteoglycan Aggregate : Structure and Function
• Proteoglycans of Cartilage Extracellular Matrix(Advances in Connective Tissue Research in Bone and Joint)

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