Roles of Proteoglycans in Neuronal Circuit Formation of Retinotectal Projections(<Special Issue>Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)

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概要

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• The formation of neuronal circuits has long been considered as one of the basic problems in the developmental neurobiology; projections from the retina to their higher center, the tectum in non-mammalian vertebrates and the superior colliculus in mammals, are the most feasible for the experimental approaches. The recent investigations have shown that a series of guidance cues along the pathways sequentially navigates the retinal axons step by step. At the decision points along the retinal pathway, steering of the retinal axons is controlled by proteoglycans and their carbohydrate chains: chondroitin sulfate proteoglycans and heparan sulfate proteoglycans.

• 日本結合組織学会の論文
• 2003-03-25

著者

• Ichijo Hiroyuki

  Department Of Anatomy Institute Of Basic Medical Sciences University Of Tsukuba

関連論文

• Roles of Proteoglycans in Neuronal Circuit Formation of Retinotectal Projections(Roles of Extracellular Matrix in the Development and Regeneration of Nervous Systems)

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