14才の少年にみられたMucopolysaccharidosis(酸性ムコ多糖代謝異常症)を伴う高度の歯周病について

概要

論文の詳細を見る
Mucopolysaccharidosis is an autosomal recessively inherited storage disease, characterized by a clinical picture of dwarfism, grotesque facies, hepatosplenomegaly, joint contractures, corneal clouding, mental retardation, vascular and endocardial disease, and early death. Excess amounts of acid mucopolysaccharide accumulate in affected organs, and are excreted in the urine of patients with the disease. A 14 year old boy who had been suffering from mucopolysaccharidosis with gingival hypertrophy, was observed. Acid mucopolysaccharides were isolated from his gingiva and urine, then investigated by chemical analysis and electrophoresis on cellulose acetate strips. The results of this experiment suggested that there there may be some relation between periodontal disease and mucopolysaccharidosis.
特定非営利活動法人日本歯周病学会の論文
1977-12-28