牛の実験的ワラビ中毒症における出血性素因に関する研究 : II. 血中ヘパリン様物質量について

概要

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Quantitative determination of the blood level of a heparin-like substancewas made using a group of three calves with experimentally-induced bracken poisoning.The average blood level of the heparin-like substance in eight normal calves was 3.2+0.95 jtg / mZ (mdhn -4- s.d.). The blond level 61 the hepaririLIikc substance exceeded 6.0 7tg /mZ in all the affected animals in the hemorrhagic stage. It did not increase in the initialstage, when the clotting time prolonged mildly. This was due to the effect of a decreasein the platelet count observed in this stage. It was very likely that the prolonged clottingtime in the hemorrhagic stage might have been caused by the synergistic etrect of anincrease in the blood level of the heparin-like substance and the stimulated sensitivity ofthe affected blood to the heparin-like substance as a result of the decrease in the plateletcount.
社団法人日本獣医学会の論文
1975-08-25