肝蛭寄生牛肝臓の病理組織学的研究特に光輝細胞と組織肥満細胞について

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In 1963, Shirai reported that brilliant cells (discox ered by Hamazaki in1935) were demonstrable in the liver of cattle infected witla Fasciola hepatica. The presentstudy was carried out to investigate an interrelationship beLwcen these and tissue mastcells. Areas of adenomatous epithelial proliferation of the bite ducts were chosen formicroscopic and histochemical sttuclies.Mast cells and brilliant cells were identified in areas of adctaomatous proliferation ofthe biliary epithelium. The brilliant cells were found to have lceen derived from smoothmuscle cells. and were classified, according to the degree of maturation and aging, intojuvenile, matture, senile and superannuating types. Both metachromatic and ketoenolicgranules (KEG) diminished progressively in number, as the cells approached senescence.Eventually, the granules disappeared altogether and were replaced by large eosinophilicdroplets (Fig. l-B). The metachromatic granules contained in mast cells were found tohave undergone virtually identical changes.The present observation indicated that the brilliant cells were originated from smoothmuscle. It was concluded tltat brilliant cells have usually been confused with mast cellsin the liver of cattle infected with Fasciola hepatica.
社団法人日本獣医学会の論文
1976-04-25