抗生物質による牛肉の腐敗防止に関する研究

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概要

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• We investigated the ability of certain antibiotics to delay spoilage in beef. The wholebeef carcass was treated by a 30 minutes dip in a fresh solution containing 10 or 50 7/mlAureomycin, Terramycin, Tetracycline or Chloromycetin prior to holding it at roomtemperature (20-3OC) ttntil spoiled.I. The bacterial growth in beef was greatly inhibited and the spoilage was retardedabout I or 2 days by dipping in a solution containit?g 10 or 50 7/llll of Aureomycin.2. The bacterial growth in beef was considerably inhibited and the spoilage wasretarded about 1 day with 10 or 507/ml Terram)rcin solvation.3. The bacterial growth in beef was considerably inhibited and the spoilage wasretarded about I or 2 days with a solution containing [0 or 50 T/ml of Tetracycline.4. The bacterial growth irm beef was greatly inhibited and the spoilage was retardedabout 1-2 clays with 107/ml and 2-3 days with 507/ml Chloromycetin solution.5. The 30 minutes dip in a 50 1/ml Aureommycin solution would not seem to promotethe development of drug-resistant s..rains in the beef. In regard to the histopathological changes in the case of infectious anemia, in horses,at has been recognized that the active changes in the reticulo-endothelial system, thatis, the swelling, the proliferation and the hemosiderosis of the R.E.S. are observed togetherwith great destruction of the red corpuscles, especially in the liver and spleen etc..""It was found by means of our new complement fixation test" that the ferritin whichwas originally the storage iron in the reticulo-endothelial system, was contained in thesera of the jugular veins of horses having infectious anemia.It may be considered that such observation of the free ferritin in the sera meansthe degeneration and the collapse of the reticulo-endothelial system, mainly in the spleen,next in the liver and the bone marrow.In this report, from such a consideration, we made observations on the correlation.among the complement fixation tests on free ferritin in tlte sera, the histopathologicalchanges and the progress of the disease, mainly in the case of infectious anemia inhorses.lhe results are summarized as follows :I) Both, in the horses from the slaughter-house, having infectious anemia, and inthe artificially anemia-infected horses, it was found that the prosperity and decline ofthe free ferritin was very closely related to the histopathological changes in the reticulo-.endothelial system, especially in the liver and spleen, that is, the swelling and prolife-

• 社団法人日本獣医学会の論文
• 1959-04-30

著者

• 大嶋 竹一

  東京大学医学部細菌学教室

• 氏家 冬深

  東京大学医学部細菌学教室

関連論文

• 抗生物質による牛肉の腐敗防止に関する研究
• 食餌成分と腸内菌叢の研究 : VI. 母乳栄養期及び離乳期における腸内菌叢
• 食餌成分と腸内菌叢の研究 : V. 蔗糖又はデキストリン加全粉乳の腸内菌叢に及ぼす影響
• 食餌成分と腸内菌叢の研究 : IV. 各種動物の腸管由来大腸菌に対する抗原分析的研究

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