本邦数カ所から採集したドブネズミ, Rattus norvegicus, に対するワルファリンの殺そ効力

概要

論文の詳細を見る
To determine the susceptibility of the wild Norway rat, Rattus norvegicus, to warfarin, a no-choice feeding test with a bait containing 0.005% warfarin was carried out using wild Norway rats collected from several places of Japan from 1981. So far as the results obtained, mean days to death in both Norway rats of most test localities and laboratory rats were approximately within five days and this values seem to indicate a standard susceptibility of Norway rats in Japan. On the other hand, susceptibility of a Norway rat population of Yumenoshima to warfarin was measured using WHO procedure, and LFP_<50>, LFP_<98> and its upper 95% confidence limit were calculated by Litchfield and Wilcoxon method. These values were 1.85,7.9 and 12.1 days, respectively, of the three, the latter two were longer than those of warfarin-susceptible populations in Europe and U. S. A. The Norway rat population of Yumenoshima could be controlled with 0.025% warfarin in 1983. Therefore, a feeding period on 0.005% warfarin to detect the appearance of warfarin-resistant strain in Japan should be investigated, although a six-day feeding test has been adopted usually in Europe and U. S. A.
日本衛生動物学会の論文
1985-06-15