Biological Monitoring of Inorganic Mercury in Workers in a Fluorescent Lamp Plant

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Biological Monitoring of Inorganic Mercury in Workers in a Fluorescent Lamp Plant. Masako IDEN, et al. Matsushita Electronics Corp., Okayama Factory-The level of mercury in urine is meacured as an exposure monitoring of mersury, and the activity of urinary N-ecetyl-β-D-glucosaminidase (NAG) is used as an index of adverse effects of mercury on human kidneys. Here we examined the validity of these prosedures by comparing the urinary total mercury (U-Hg) level and NAG activity both 75 male workers exposed to inorganic mercury and age-matched unexposed male workers in a fluorescent lamp plant. To investigate factors affecting the levels of U-Hg, 12 items were selected in relation to oral intake and excretion of mercury : consumption of 1) soft drink, 2)coffee or tea, 3)milk and 4)alcohol ; 5) habit of drinking tap water at the work place ; frequency of 6) eating fish and 7) alcohol intake ; 8) smoking : 9) use of dental amalgam ; 10) eating of home grown rice ; 11) exercise habit and 12) age. The U-Hg level and NAG activity were adjusted by creatinine levels. Personal exposure levels of inorganic mercury in air (A-Hg) and the U-Hg level correlated well (p<0.001) in the exposed group but neither the exposed nor unexposed group showed a correlation between the U-Hg level and NAG activity. Although the mean level of U-Hg in the exposed group was higher than that in the unexposed (p<0.001), no difference was observed in the mean level of NAG activity. A multiple regression analysis followed by a one-way ANOVA revealed that only the frequency of eating fish per week contributed to increase the level of U-Hg. The results suggest that oral intake of mercury from fish is a possible confounding factor in the exposure monitoring of inorganic mercury in the work place.
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Biological Monitoring of Inorganic Mercury in Workers in a Fluorescent Lamp Plant

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