Effects of Hair Dyeing on DNA Damage in Human Lymphocytes

概要

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Comet assays were carried out to evaluate DMA damage in human lymphocytes from 20 volunteers before and after hair dyeing. DMA damage in lymphocytes was found to be slightly higher in volunteers after hair dyeing. Tail moments before and after hair dyeing were 1.47 ± 0.41 and 1.75 ± 0.29 respectively (p<0.0008). DMA damage in lymphocytes showed significant difference with treatment and heating time. The tail moments after 15 min of treatment time before and after hair dyeing were 1.44 ± 0.22 and 1.85 ± 0.36, respectively (p=0.0004) and the corresponding tail moments in 20 min of heating time before and after were 1.37 ± 0.15 and 1.78 ± 0.34 (p=0.0002). In conclusion, we found that an acute exposure of hair dyes with heating caused DMA damages in peripheral lymphocytes and that this damage had significant association with treatment and heating time.
社団法人日本産業衛生学会の論文