Relationships between the effect of O_2 on energy metabolism and RNA synthesis in Rhodotorula gracilis

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概要

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• In the aerobic yeast Rhodotorula gracilis, a decrease in O_2 availability, from saturating conditions (pO_2=100 mm Hg) to pO_2=1 mm Hg, causes a decrease in the growth rate accompanied by a fall in the accumulation rate of RNA and, to a lesser extent, of proteins. At pO_2=1, no relevant changes in the levels of triphosphate nucleotides (ATP, GTP, CTP and UTP) are observed with respect to the controls, while the ADP and AMP levels markedly increase. The uptake of labelled precursors and qualitative analysis of RNA suggest that the decrease in the RNA accumulation rate at pO_2=1 is due to a decreased RNA synthesis rate. This paper examines the mechanism by which low availability of O_2 causes a decrease in the RNA synthesis rate even though total triphosphate nucleotide levels remain high.

• 日本植物生理学会の論文

著者

• Cocucci Maurizio

  Centro De Studio Del C.n.r. Per La Biologia Cellulare E Molecolare Delle Piante Institute De Scienze

関連論文

• Relationships between the effect of O_2 on energy metabolism and RNA synthesis in Rhodotorula gracilis

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