A New Method to Modify the C-4 Position of 10-Deacetylbaccation III
スポンサーリンク
概要
- 論文の詳細を見る
We have developed a new method to modify the C-4 position of 10-deacetylbaccatin III (5) using the C-4 acetoxy anion of the 13-keto derivative (7) and various alkyl halides. The method developed herein shound be very useful for the preparation of C-4 modified taxoid analogs.
- 公益社団法人日本薬学会の論文
- 1997-12-15
著者
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Uoto K
Medicinal Chemistry Research Laboratory Daiichi Pharmaceutical Co. Ltd. Tokyo R&d Center
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Terasawa H
Medicinal Chemistry Research Laboratory Daiichi Pharmaceutical Co. Ltd. Tokyo R&d Center
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Soga T
Medicinal Chemistry Research Laboratory Daiichi Pharmaceutical Co. Ltd. Tokyo R&d Center
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UOTO Kouichi
New Product Research Laboratories IV, Daiichi pharmaceitucal Co., Ltd.,
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TAKENOSHITA Haruhiro
New Product Research Laboratories IV, Daiichi pharmaceitucal Co., Ltd.,
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TERASAWA Hirofumi
New Product Research Laboratories IV, Daiichi pharmaceitucal Co., Ltd.,
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SOGA Tsunehiko
New Product Research Laboratories IV, Daiichi pharmaceitucal Co., Ltd.,
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ISHIYAMA Takashi
New Product Research Laboratories IV, Daiichi Pharmaceutical Co., Ltd.,
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Ishiyama Takashi
New Product Research Laboratories Iv Daiichi Pharmaceutical Co. Ltd.
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