10-Bromocamphorに対するアルカリ性物質の作用(第1報)

概要

論文の詳細を見る
On treatment with ammonia, 10-bromocamphor gave d-α-campholenic amide which, on treatment with hydrochloric acid, stereochemically isomerized to the levorotatory amide. As a means of studying the principle that underlies this transformation, isomerization was attempted on original α-campholenic acid with mineral acid. It was clarified from infrared absorption spectra that the double bond in the case of alkali-formed products, is situated in a methylene group outside the cyclopentane ring and, in the case of acid-treated products, inside the ring. The former was termed α-campholenic acid-I and the latter α-campholenic acid-II. The properties of α-campholenyl alcohol-I and -II, formed by the respective reduction of the esters of acid-I and -II, were determined.
公益社団法人日本薬学会の論文
1956-12-20