トリメチルピラチン誘導体の合成と抗菌作用
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概要
- 論文の詳細を見る
Some 2-substituted-3,5,6-trimethylpyrazine derivatives were synthesized from 2-chlorotrimethylpyrazine and, by their antibacterial tests, 2-mercapto and 2-(p-nitrophenylsulfonyl) derivatives were found to have antibacterial activities against gram-positive bacteria (Staphylococcus aureus). 2-Sulfanilamido derivative exhibited the same minimum inhibitory concentration against gram-negative bacteria (Eschericherichia coli) as against gram-positive bacteria (Staphylococcus aureus).
- 公益社団法人日本薬学会の論文
- 1967-01-25