血液中の白血球, 血小板除去方法について
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概要
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Ion-exchange celluloses and resins, silicic acids, cellulose fibers, and cotton wool were tested as adsorbents for leukocytes and platelets in whole blood and packed red cell suspension. Among the adsorbents tested, KC-Flock W-50S, Avicel PH101,and cotton from Gossypium barbadense were effective for removing leukocytes and platelets. When 3 column volume of blood was passed through a column packed with cellulose fibers, KC-Flock W-50S, 97% of leucocytes and 88% of platelets were removed. Recovery of red cells was quantitative. Efficacy of various adsorbents tested is discussed. Roughness and large surface area seem to be requisite factors for effective adhesion of leukocytes and platelets.
- 公益社団法人日本薬学会の論文
- 1978-04-25