鶯糞より分離した一糸状菌のウリカーゼ生産特性(第1報)高塩濃度および亜鉛塩によるウリカーゼ生成促進

概要

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A Hyphomycetes, strain F1,isolated from the excrements of Cettia diphone cantans was found to have the following characteristics on uricase production. 1) This strain was resistant to a high concentration of KCl or NaCl, and the addition of about 4.0% of these salts to the medium gave the maximum uricase production, which the was about two times in dry weight of the pellicle and about 15 times in the amount of enzyme compared to the normal fungal medium containing 0.05% of the salts. 2) The zinc-salt was found to be the only accelerator for the uricase production by this strain after detailed examination of various metal salts. Maximum uricase production was obtained by incubating this strain for 5 days in the medium containing 0.001-0.01 % of ZnSO_4・7H_2O or ZnCl_2,when the amount of the enzyme was increased 3-4 fold compared to the absence of zinc salt.
公益社団法人日本薬学会の論文
1976-01-25