長鎖アルキル第3級アミンとエピクロルヒドリンの反応
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概要
- 論文の詳細を見る
The reaction of long chain alkyltertiaryamines and epichlorohydrin, in the presence of an organic acid, was followed. In the absence of an organic acid, the reaction in alcohol (ethanol-) or benzene gave 2,5-(p-dioxyanylene)-bismethylene-bis (trialkylammonium chloride). In the presence of picric acid or sulfonic acid, 3-chloro-2-hydroxypropyltrialkylammonium salts were formed. In the presence of phenols or carboxylic acids, the acid residue was found to combine in ether or ester form to produce 3-phenoxy- or 3-acyloxy-2-hydroxypropyltrialkylammonium chloride. In the presence of acetylacetone, 2-hydroxypropylene-1,3-bis (trialkylammonium chloride) was formed in 24-29% yield.
- 公益社団法人日本薬学会の論文
- 1973-10-25