1-Phenyl-1-hydroxy-n-pentaneのヒトにおける代謝(第1報) : 尿中排泄および代謝物について
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概要
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After oral administration of 300 mg of 1-phenyl-1-hydroxy-n-pentane (PHP), which increases pancreatic and biliary secretion, to each of three human subjects, its urinary excretion and metabolites were examined by gas chromatography. Excretion of PHP and PHP-glucuronide in the first 4 hr urine was below 1% and 35-37%, respectively, of the dose administered. The amount of both the compounds in urine was very small during 8-48 hr after oral administration.
- 公益社団法人日本薬学会の論文
- 1972-03-25