N-アセチルシステイン抱合体の新代謝経路関連酵素を中心として

概要

論文の詳細を見る
Mercapturic acids (N-acetylcysteine conjugates) are converted to methylthio-containing metabolites by the action of several enzymes ; deacetylases for mercapturic acids, C-S lyases for cysteine conjugates, aminotransferase for cysteine conjugates, C-S lyase for thiopyruvic acid conjugates, and methyltransferases for thiols. Methylsulfides thus formed are subsequently oxidized to methylsulfoxides or methylsulfones prior to excretion. In some cases methylsulfoxides are susceptible to enzymatic reduction.
社団法人日本薬学会の論文
1987-01-25