Neomycin Bをリード化合物とした抗HIV薬の合成研究
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概要
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Neomycin B has been found to block the binding of HIV-1 Rev protein to its viral RNA recognition site, thereby inhibiting the production of the virus. This paper describes the synthesis of analogues of neomycin B, which are potential anti-HIV compounds designed as inhibitors of Rev/RRE binding.
- 公益社団法人日本薬学会の論文
- 2002-07-01