有機燐製剤の中毒防止に関する研究(I)

概要

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In Spite of the recent development in making less poisonous pesticides, there have been still a large number of accidents caused by the pesticides. We performed the determination of activity of acetyl choline esterase in blood of ca. 10,000 persons who were handling organophosphorous pesticides. The Ishido-(Keio University)-method was employed for the determination. The results could be summerized as follow. (1) Poisonous : 3.62%, Critical, in spite of lacking symptoms : 17.82%, Normal : 78.56%. (2) The activity of the esterase was apt to be lowered more easily in female than in male. (3) The lowering was more evident in older persons. (4) The lowering was intense in wet season during which there could be many chances to handle pesticides. (5) Some relationships were found between the number of poisoning cases and of yeas of their handling-experiences.
公益社団法人日本薬学会の論文
1964-03-30