最近の裁判化学における薬毒物分析の動向

概要

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This review surveys various chromatographic methods for the extraction and the determination of drugs and toxic compounds in biological and environmental materials reported during 1980-1985. The column liquid chromatographic methods by use of XAD-2,XAD-4,Extrelut, Clin Elut (Chem Elut), Sep Pak C_<18>, Bond Elut, Bio Beads SX-2 and SX-3 gel were applied to simple and rapid extraction and clean up of drugs and toxic compounds in biological and environmental materials. These chromatographic methods include high performance thin-layer chromatography, capillary gas chromatography, capillary gas chromatography-mass spectrometry (GC-MS), high performance liquid chromatography (HPLC) with photodiode array detection, high performance liquid chromatography-mass spectrometry, and isotachophoresis. Trace drugs and toxic compounds in biological and environmental materials were rapidly, sensitively and selectively detectable by HPLC with photodiode array detection, and capillary GC-MS.
1986-06-30