Determination of Methamphetamine in Human Urine by HPLC Using Post-Column Simon's Reaction
スポンサーリンク
概要
- 論文の詳細を見る
An HPLC method using post-column Simon's reaction (SR-HPLC) for the determination of methamphetamine (MA) has been developed. The detection limit was 1ng, which is about 100 times more sensitive than TLC using Simon's reaction (SR-TLC). The calibration curve was linear in the range of 0.1-1000μg/ml, and the intermediate precision of within-run and between-run assays was 1.15% and 2.12%, respectively. MA in 13 urine samples was determined by SR-HPLC and GC with flame ionization detection, and these quantitative values were strongly correlated (r^2=0.995). MA could be analyzed without interference peaks. The proposed method is highly selective and quantitative.
- 公益社団法人日本薬学会の論文
- 2000-02-01
著者
-
Ueda K
Kanazawa Univ. Kanazawa Jpn
-
Ueda Kazumasa
Department Of Chemistry And Chemical Engineering Kanazawa University
-
Ueda Kazumasa
Department Of Chemistry And Chemical Engineering Faculty Of Engineering Kanazawa University
-
Chinaka Satoshi
Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters
-
Tanaka Seishi
Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters
-
Takayama Nariaki
Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters
-
Tanaka Seishi
Forensic Science Laboratory Ishikawa Prefectural Police Headquarters
-
Takayama Nariaki
Forensic Sci. Lab. Ishikawa Prefectural Police Headquarters
-
Chinaka Satoshi
Forensic Science Laboratory Ishikawa Prefectural Police Headquarters
-
Ueda Kazumasa
Department of Chemistry and Chemical Engineering, Faculty of Engineering, Kanazawa University
関連論文
- Determination of Minor and Trace Elements in Biogenic Carbonate Minerals of Coccolithophores by High-Resolution Inductively Coupled Plasma Mass Spectrometry
- PHOTOSYNTHESIS REGULATION OF PHYTOPLANKTON BY ORGANIC COMPLEXATION OF IRON
- A Fast and Simple Analysis of Glyphosate in Tea Beverages by Capillary Electrophoresis with On-Line Copper(II)-Glyphosate Complex Formation
- Highly Efficient Chromatographic Optical Resolution of fac-Tris(β-alaninato)cobalt(III) with an Optically Active ob_3 Isomer of Tris(trans-1,2-diaminocyclohexane)cobalt(III) Cation Adsorbed on a Cation-Exchange Resin
- Preparations and Spin-spin Interactions of 4,4′-(Triptycene-1,8-diyl) bis (1-methyl-2,6-diphenylpyridinyl) Diradical and Its 1,5-Diyl Isomer
- Determination of Methamphetamine in Human Urine by HPLC Using Post-Column Simon's Reaction
- Simultaneous determination of cyanide and thiocyanate in blood by ion chromatography with fluorescence and ultraviolet detection
- Analysis of Phosphorus-containing Amino Acid-type Herbicides by Capillary Electrophoresis/Mass Spectrometry Using a Chemically Modified Capillary Having Amino Groups
- High-Sensitivity Analysis of Cyanide by Capillary Electrophoresis with Fluorescence Detection
- Distribution analysis of epoxy groups in polymers by derivatization-electron probe x-ray microanalysis
- Distribution analysis of hydroxyl groups in polymers by derivatization-electron probe X-ray microanalysis
- Chiral Capillary Electrophoresis of Agrochemicals in Real Samples
- Chiral Capillary Electrophoresis of Amphetamine-Type Stimulants
- Simultaneous Chiral Analysis of Methamphetamine and its Metabolites by Capillary Electrophoresis/Mass Spectrometry with Direct Injection of Urine
- Simultaneous Chiral Analysis of Methamphetamine and Related Compounds by Capillary Electrophoresis/Mass Spectrometry Using Anionic Cyclodextrin
- Analysis of Reaction Products of Morphine and Codeine with Hydrogen Peroxide by High-Performance Liquid Chromatography/Mass Spectrometry
- Molecular Phylogeny in the Lardizabalaceae
- Analysis of Phosphorus-containing Amino Acid-type Herbicides by Sheathless Capillary Electrophoresis/Electrospray Ionization-Mass Spectrometry Using a High Sensitivity Porous Sprayer
- Determination of trace amounts of iron, nickel, and tin in zircaloys by X-ray fluorescence spectrometry after coprecipitation with hexamethyleneammonium hexamethylenedithiocarbamate.
- The extraction spectrophotometric determination of cobalt(II) with 4-(2-thiazolylazo)resorcinol and zephiramin.
- Selective extraction spectrophotometric determination of iron by utilizing the peculiar absorption of iron(II)-2-(2-thiazolylazo)-5-dimethylaminophenol complex.
- Synthesis, Electronic, and Crystal Structures of Methoxycarbonyl-substituted 2,5-Di(1,3-dithiol-2-ylidene)-1,3-dithiolane-4-thione Derivatives