Thermodynamic Studies of the Charge-Transfer Interactions of Chloranilic Acid with Moclobemide and Promethazine Hydrochloride

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概要

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• Spectrophotometric absorption studies geve evidence for the formation of strongly bonded charge-transfer complexes between moclobemide and promethazine hydrochloride with chloranilic acid in non-aqueous media comprising chloroform and 1,4-dioxane. The transitions involved were detected at wavelengths longer than those of the single pure substances in the visible region. Equilibrium constants from the Scott equation could be measured together with other thermodynamic parameters and molar absorptivities at different temperatures. Theoretical arguments are presented as to the spontaneity of these interactions.

• 公益社団法人日本薬学会の論文
• 1998-12-15

著者

• Adikwu M

  Univ. Nigeria Enugu State Nga

• Attama A

  Drug Delivery Research Unit Department Of Pharmaceutics University Of Nigeria

• ADIKWU Michael

  Department of Pharmacokinetics, Kyoto Pharmaceutical University

• OFOKANSI Kenneth

  Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria

• ATTAMA Anthony

  Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria

• Adikwu Michael

  Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences University Of Nigeria

• Attama Anthony

  Division Of Physical Pharmaceutics Faculty Of Pharmaceutical Sciences University Of Nigeria Nsukka

• Ofokansi Kenneth

  Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences University Of Nigeria

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