EVALUATION OF PSK, AN ANTITUMOR PROTEIN-BOUND POLYSACCHARIDES, BY THYMOCYTE ELECTROPHORESIS

スポンサーリンク

概要

• 論文の詳細を見る

• It was clear that the proportion of high mobility cells in thymus tended to increase during tumor development by cell electrophoresis. Although the antitumor activity of PSK, protein-bound polysaccharide or mitomycin-C was similarly effective in sarcoma-180-bearing mice, the histogram pattern of thymocyte electrophoresis differed markedly from each other. Normally, the proportion of high mobility cells of thymocyte increased more with the administration of mitomycin-C than that of the untreated tumor-bearers, while PSK kept the thymic cell mobility histogram normal. Changes of thymocyte electrophoresis caused by the drugs also correlated with the depression of their antiinfectious activity. Using the fully automated cell electrophoretic instrument, the drug can be evaluated simply from the viewpoint of antiinfectious efficacy.

• 公益社団法人日本薬学会の論文

著者

• Mori Tomoko

  Department Of Pharmacology School Of Pharmacy Hoshi University

• Mori Takeo

  Department Of Surgery Tokyo Metropolitan Komagome Hospital

• IWAGUCHI TAKAO

  Department of Cancer Therapeutics, The Tokyo Metropolitan Institute of Medical Science

• Iwaguchi Takao

  Department Of Cancer Therapeutics The Tokyo Metropolitan Institute Of Medical Science

• Iwaguchi Takao

  Department Of Cancer Therapy Tokyo Metropolitan Institute Of Medical Science

• KOHSAKI GORO

  Department of Surgery, Tokyo Metropolitan Komagome Hospital

• Kohsaki Goro

  Department Of Surgery Tokyo Metropolitan Komagome Hospital

関連論文

• EVALUATION OF ANTICANCER DRUGS BY LYMPHOCYTE ELECTROPHORESIS
• HPV infection in an HIV-positive patient with primary squamous cell carcinoma of rectum
• Overexpression of soluble vascular endothelial growth factor receptor 1 in colorectal cancer : Association with progression and prognosis
• Assessment of SMAD4, p53, and Ki-67 Alterations as a Predictor of Liver Metastasis in Human Colorectal Cancer
• Alveolar Echinococcosis of the Liver in a Tokyo Resident with an Unknown Route of Infection : Report of a Case
• Effects of L-Tryptophan on the Effects of Antitussives
• EVALUATION OF PSK, AN ANTITUMOR PROTEIN-BOUND POLYSACCHARIDES, BY THYMOCYTE ELECTROPHORESIS
• Significance and limit of lymph node dissection : efficacy of combined modalities
• Characterization of Suppressor T-Cells Induced with Concanavalin A in Vivo by Cell Electrophoresis

スポンサーリンク