BILAYER MEMBRANE FORMATION IN THE CHENODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION

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概要

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• The physicochemical process whereby bilayer membranes are formed in the chenodeoxycholate, phosphatidylcholine and cholesterol solution is described. Observations were made by electron microscopy using both the negative stain method and the freeze fracture method after excess amounts of cholesterol monohydrate crystals were incubated at varying ratios in sodium taurochenodeoxycholate and phosphatidylcholine solutions. A hypothesis of the transformational processes from bilayer disk to multilamellar liposome in the artificial bile is presented.

• 公益社団法人日本薬学会の論文

著者

• Igimi Hirotsune

  First Department Of Surgery

• Murata Kunihiko

  Central Laboratory For Infectious Diseases

関連論文

• BILIARY EXCRETION OF LATAMOXEF AND N-METHYLTETRAZOLETHIOL IN HUMANS AND RATS
• BILAYER MEMBRANE FORMATION IN THE CHENODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION
• THE DEVELOPMENTAL PROCESS FROM MICELLE TO LIQUID CRYSTAL IN THE URSODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION

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