ENZYME IMMUNOASSAY FOR METHAMPHETAMINE

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概要

• 論文の詳細を見る

• A competitive enzyme immunoassay for methamphetamine with alkaline phosphatase labeled methamphetamine, Sepharose-antibody and p-nitrophenylphosphate as substrate was developed. The anti-methamphetamine antisera produced in rabbits by immunization with N-(4-aminobutyl) methamphetamine-BSA conjugate were specific for methamphetamine and showed low cross-reactivities with p-OH methamphetamine and amphetamine (metabolites of methamphetamine). The range of methamphetamine measurable by the enzyme immunoassay was 1 to 300 ng/tube. According to the assay, methamphetamine could be detected from urine and extract of hair.

• 公益社団法人日本薬学会の論文

著者

• Aoki Kimiko

  Faculty Of Pharmaceutical Sciences Showa University

• Kuroiwa Yukio

  Faculty Of Pharmaceutical Sciences Showa University

• KUROIWA YUKIO

  Faculty of Pharmaceutical Sciences, Showa University

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