Preparation of Novel Synthons, Uniquely Functionalized Tetrahydrofuran and Tetrahydropyran Derivatives
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概要
- 論文の詳細を見る
The dianion of the acetoacetic ester reacts with epibromohydrin derivatives to affored a mixture of (Z)-2-alkoxycarbonylmethylidenetetrahydrofuran derivative and (E)-2-alkoxycarbonylmethylidenetetrahydropyran derivative. The selective formation of the tetrahydrofuran derivative is achieved by the use of LiClO_4 as the additive. The preparation of the optically active tetrahydrofuran derivatives and tetrahydropyran derivatives is also examined, and the optical purity and absolute configuration of the products is elucidated.
- 2000-10-01
著者
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Takano Masashi
Department Of Chemistry And Biochemistry Faculty Of Science And Engineering Waseda University
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Takano Masashi
Department Of Chemistry School Of Science And Engineering Waseda University
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Nakada M
Department Of Chemistry School Of Science And Engineering Waseda University:materials Research Labor
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Nakada Masahisa
Department Of Chemistry And Biochemistry Faculty Of Science And Engineering Waseda University
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IWATA Yukitaka
Department of Chemistry, School of Science and Engineering Waseda University
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Iwata Y
Department Of Chemistry School Of Science And Engineering Waseda University
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