The Primary Structure of Toxin C from the Venom of the Indian Cobra (Naja naja)

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概要

• 論文の詳細を見る

• The primary structure of toxin C, a neurotoxin isolated from Indian cobra (Naja naja) venom, was determined. Toxin C is a highly toxic polypeptide consisting of 71 amino acid residues (molecular weight 7800) crosslinked by five disulfide bridges. A high degree of homology is observed among the long-chain neurotoxins. Toxin C differs from toxin A only in having -Ala-28 and -Lys-49 in place of -Gly-28 and -Arg-49,and from toxin B in having -Ala-28,-Ile-32 and -Lys-49 in place of -Gly-28,-Ser-32 and -Arg-49 residues. The amino acid sequence of toxin C is the same as that of Naja naja siamensis neurotoxin 3.

• 公益社団法人日本薬学会の論文
• 1981-05-23

著者

• 林 恭三

  Department of Molecular Biology, Gifu Pharmaceutical University

• 佐々木 豊作

  京都大学薬学部

• 太田 光照

  Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Kyoto University

• 佐々木 豊作

  Himeji Institute of Technology

• 太田 光照

  Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Kyoto University

関連論文

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• インドコブラ細胞毒Iiaのアミノ酸配列
• The Primary Structure of Toxin C from the Venom of the Indian Cobra (Naja naja)

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