Studies on Antiviral Glycosides : V. Formation of Incomplete Sendai Virions in the Presence of Phenyl-6-chloro-6-deoxy-β-D-glucopyranoside

概要

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Addition of phenyl-6-chloro-6-deoxy-β-D-glucopyranoside (PCG) to culture cells before infection with Sendai virus resulted in the production of incomplete virions defective in biological activities as well as infectivity. These noninfectious virions were characterized by chemical and physical methods. Electrophoretic analysis by SDS-PAGE showed differences in the M-protein region between the intaot and incomplete virions, although no morphological differences were observed by electron microscopy.
公益社団法人日本薬学会の論文
1981-10-25