Synthesis and Structure-Activity Relationship of Trimebutine Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
Trimebutine derivatives were synthesized by utilizing alkylation or acylation of isonitriles and nitrile as a key step. The colonic contractile effects of these compounds were examined, and T-1815 was found to have strong colonic propulsive activity.
- 社団法人日本薬学会の論文
- 1996-06-15
著者
-
Sai H
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd.
-
SAI Hiroshi
Lead Optimization Research Laboratory, Tanabe Seiyaku Co., Ltd.,
-
OZAKI Yasuhiko
Pharmaceutical Development Research Laboratory, Tanabe Seiyaku Co., Ltd.,
-
HAYASHI Kimiaki
Pharmaceutical Development Research Laboratory, Tanabe Seiyaku Co., Ltd.,
-
ONODA Yuichi
Lead Optimization Research Laboratory, Tanabe Seiyaku Co., Ltd, .,
-
YAMADA Kenji
Lead Optimization Research Laboratory, Tanabe Seiyaku Co., Ltd.,
-
Sai Hiroshi
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd.
-
Onoda Y
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd .
-
Ozaki Yasuhiko
Pharmaceutical Development Research Laboratory Tanabe Seiyaku Co. Ltd.
-
Hayashi Kimiaki
Pharmaceutical Development Research Laboratory Tanabe Seiyaku Co. Ltd.
-
Yamada Kenji
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd.
関連論文
- Synthesis and Structure-Activity Relationship of Trimebutine Derivatives
- Conformational Analysis of Model Polypeptides Having Repetitive Glu-Pro-Pro-Pro Sequences
- Preparation of (2S, 3S)-2,3-Dihydro-3-Hydroxy-2-(4-Methoxyphenyl)-1,5-Benzothiazepin4-(5H)-One by Microbial Conversion
- Conformational Analysis of Polypeptides Having Repetitive Xaa-Xaa-Pro Sequences