Facile and Useful Synthesis of Enantiomeric Phosphatidylcholines

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概要

• 論文の詳細を見る

• The synthesis of optically active phosphatidylcholines (D- and L-4) containing two of the same fatty acid moieties in a molecule is described. Optically pure D-enantiomers (D-4) were obtained from 2,3-di-O-acyl-sn-glycerol (D-1) in high yield by phosphorylation with phosphorus oxychloride and subsequent treatment with choline tosylate (11a). L-Enantiomers (L-4) were also prepared in a similar manner from 1,2-di-O-acyl-sn-glycerol (L-1). The whole procedure is easy and useful for the synthesis of enantiomeric phosphatidylcholines.

• 公益社団法人日本薬学会の論文
• 1996-05-15

著者

• Sano Atsunori

  Tokyo Research Laboratories Wako Pure Chemical Industries Ltd.

• ISHIHARA Masami

  Tokyo Research Laboratories, Wako Pure Chemical Industries, Ltd.,

• Ishihara Masami

  Tokyo Research Laboratories Wako Pure Chemical Industries Ltd.

関連論文

• Facile and Useful Synthesis of Enantiomeric Phosphatidylcholines

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