Adsorption and Desorption of Indomethacin on Cellulose-like Biopolymers : Chitin and Chitosan

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概要

• 論文の詳細を見る

• The adsorption-desorption effect of cellulose-like biopolymers such as chitin and chitosan, and microcrystalline cellulose on indomethacin was investigated. The adsorptive capacity was ranked in the order : chitosan>chitin>microcrystalline cellulose. All the adsorption isotherms were found to follow Langmuir and Freundlich equations. However, chitosan-acetate gel powders and chitosan powders with pre-added acetic acid and methanol did not follow these equations, due to gel formations that led to more adsorption of indomethacin on the interlayer space of the gel. The strong adsorption of chitosan might result in difficult desorption of indomethacin.

• 公益社団法人日本薬学会の論文
• 1992-04-25

著者

• 林 山陽

  Biopharmaceutics Laboratory Department Of Medical Research Veterans General Hospital-taipei

• 彭 仁瑛

  Biopharmaceutics Laboratory, Department of Medical Research, Veterans General Hospital-Taipei

• 彭 仁瑛

  Biopharmaceutics Laboratory Department Of Medical Research Veterans General Hospital-taipei

関連論文

• Zero-Order or First-Order Release Kinetics of Water-in Oil-in-Water (W/O/W) Multiple Emulsions of Lipiodol Dependent on the Types of Surfactants
• Effect of Acid Type, Acetic Acid and Sodium Carboxymethyl Cellulose Consentrations on the Formation, Micromeritic, Dissolution and Floating Properties of Theophylline Chitosan Microcapsules
• Adsorption and Desorption of Indomethacin on Cellulose-like Biopolymers : Chitin and Chitosan

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