Antiproliferating Polyquinanes. VI. : Synthesis of 2-Methylene[3.3.3]propellan-3-one Derivatives with Hydrophilic Groups

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概要

• 論文の詳細を見る

• New analogues related to 2-methylenetricyclo[3.3.3.0]undecan-3-one (4), which shows potent antiproliferating activity, i.e., 2-(methoxymethoxy)-4-methylenetricyclo[3.3.3.0]undecan-3-one (5), (1S^*, 5R^*, 7S^*)-7-(methoxymethoxy)- and hydroxy-2-methylenetricyclo[3.3.3.0]undecan-3-ones (6 and 7), and (1S^*, 5R^*, 8S^*)-8-(methoxymethoxy)- and hydroxy-2-methylenetricyclo[3.3.3.0]-undecan-3-ones (8 and 9), were readily synthesized through skeletal transformations of derivatives of tricyclo[4.3.2.0]undecan-2-one (2).

• 社団法人日本薬学会の論文
• 1988-02-25

著者

• 小廣 和哉

  Department Of Applied Fine Chemistry Faculty Of Engineering Osaka University

• 垣内 喜代三

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 上 真樹

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 永島 輝久

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 戸部 義人

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 大平 愛信

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 衣川 雅彦

  Department of Applied Fine Chemistry, Faculty of Engineering, Osaka University

• 大平 愛信

  Department Of Applied Fine Chemistry Faculty Of Engineering Osaka University

• 衣川 雅彦

  Department Of Applied Fine Chemistry Faculty Of Engineering Osaka University

• 戸部 義人

  阪大工

• 垣内 喜代三

  阪大工

• 上 真樹

  Department Of Applied Fine Chemistry Faculty Of Engineering Osaka University

• 永島 輝久

  Department Of Applied Fine Chemistry Faculty Of Engineering Osaka University

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• Antiproliferating Polyquinanes. VI. : Synthesis of 2-Methylene[3.3.3]propellan-3-one Derivatives with Hydrophilic Groups
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