Application of the Ammonia Selective Electrode : Determination of Meprobamate by Decomposition with Acid
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概要
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Meprobamate decomposes into NH_4Cl, CO_2,and a diol compound on heating in 20% HCl, and the NH_3 evolved at pH above 11 can be determined using the NH_3 selective electrode without separation from the decomposition solution. A linear calibration plot was obtained within the concentration range of 1×10^<-5>-1×10^<-2>_M meprobamate. Volatile amines and the Hg ion, which forms a metal complex with NH_3,are known to interfere with the electrode measurements.
- 公益社団法人日本薬学会の論文
- 1980-09-25
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