Inactivation of Viruses intentionally added to Urokinase Samples by Heat-Treatment
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概要
- 論文の詳細を見る
An apprehension for virus contaminant cannot be completely eliminated from urokinase (plasminogen activator) preparation originated from human urine theoretically. In this experiment the effect of heat-treatment of urokinase at 60°for 10 hr on infectivity of viruses added intentionally to urokinase samples was investigated. (1) Ten kinds of viruses used were completely inactivated within 5 hr of incubation at 60°. (2) Decrease of urokinase activity due to heat-treatment was avoided by adding albumin as a stabilizer.
- 公益社団法人日本薬学会の論文
- 1977-12-25
著者
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石川 英之
Research Laboratories Of The Green Cross Corporation
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東 昇
Department Of Microbiology School Of Medicine Kawasaki University