A Simple Method for the Measurement of the Cardiac Afferent Activities as affected by Drugs, using the Perfused Heart of the Bullfrog

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概要

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• Afferent activity from baroreceptors in the isolated heart of the bullfrog was recorded. Two types of volley were observed during the period of the cardiac cycle : a lasting volley of discharges accompanying the QRS complexes in electrocardiogram and a short volley of discharges following immediately after the P wave. Epinephrine, veratridine and ouabain caused an increase in the rate of afferent discharges from baroreceptors in the heart, whereas acetylcholine and ajmaline caused a reduction in the rate. Thus this method allowed a simple measurement of the effect of drugs on the cardiac afferent activities.

• 公益社団法人日本薬学会の論文
• 1975-09-25

著者

• 石河 醇一

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 福田 秀男

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 福田 秀男

  Faculty Of Pharmaceutical Sciences Nagoya City University

関連論文

• The Actions of N-Propyl Ajmaline on Experimental Arrhythmias and Electrophysiological Properties of the Heart
• Pharmacological Study on the Aortic Arch Baroreceptors in the Rabbit
• A Simple Method for the Measurement of the Cardiac Afferent Activities as affected by Drugs, using the Perfused Heart of the Bullfrog

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