Prediction of Stability of Drugs. IV. Prediction of Stability by Multilevel Nonisothermal Method

スポンサーリンク

概要

• 論文の詳細を見る

• For prediction of stability of drugs upon storage attended by temperature change, the multilevel nonisothermal method that estimates stability from degradation ratio after a specific period in straight temperature increase process was proposed. The theoretical consideration for this method and the development of an apparatus were made and the graphical method was employed for calculation. Several drugs were used to test this method. As a result, the values predicted by the graphic calculation were consistent with the values observed after storage in a warehouse. It is considered that the present method is a useful means for quality assurance of drugs.

• 公益社団法人日本薬学会の論文
• 1975-04-25

著者

• 大草 直也

  Technical Department, Daiichi Seiyaku Co. Ltd.

• 大草 直也

  Technical Department Daiichi Seiyaku Co. Ltd.

• 大草 直也

  Laboratory of Pharmaceutical Formulation, Research Institute, Daiichi Seiyaku Co., Ltd.

関連論文

• Stability of Drugs in Aqueous Solutions. II. Application of Weibull Probability Paper to Predictions of Coloration of Parenteral Solutions
• Prediction of Stability of Drugs. IV. Prediction of Stability by Multilevel Nonisothermal Method
• Prediction of Stability of Drugs. III. Application of Weibull Probability Paper to Prediction of Stability

スポンサーリンク