Studies on Alkylated Furan Derivatives. I. Syntheses and Antimicrobial Activity of N-Heterocyclyl-5-nitro-2-furamide. I.

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概要

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• Compounds of N-[4-(p-alkylphenyl)-2-thiazolyl]-5-nitro-2-furamide (I), N-(5-alkyl-1,3,4-thiadiazolyl)-5-nitro-2-furamide (II), and N-(6-alkoxy-3-pyridazinyl)-5-nitro-2-furamide (III) were synthesized to observe their antibacterial and antifungal activity. On the bacteria, ethyl derivative among the compounds of (I) series and, methyl and ethyl derivatives of (III) series were observed to have effects nearly equal to that of nitrofuran. Antifungal activity of the compounds of three series were more or less effective on both Trichophyton asteroides and Aspergillus fumigatus, but uneffective on the other fungi.

• 公益社団法人日本薬学会の論文
• 1962-07-25

著者

• 牧野 輝勇

  Pharmaceutical Institute Keio University

関連論文

• Studies on Alkylated Furan Derivatives. I. Syntheses and Antimicrobial Activity of N-Heterocyclyl-5-nitro-2-furamide. I.

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